Corrects sodium in hyperglycemia
Total Score
Hyponatremia.
Disclaimer: The clinical scoring and algorithms on this platform are intended strictly for professional informational purposes. They do not constitute a definitive medical diagnosis, treatment, or clinical decision. The final judgment and responsibility lie with the treating physician.
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In states of severe hyperglycemia (such as Diabetic Ketoacidosis [DKA] or Hyperosmolar Hyperglycemic State [HHS]), glucose acts as an osmotically active solute, pulling water from the intracellular space into the extracellular fluid. This dilutes the serum sodium, causing a 'pseudo-hyponatremia'. The Corrected Sodium formula reveals the true underlying sodium concentration, guiding appropriate intravenous fluid selection (e.g., Normal Saline vs. Half-Normal Saline).
The standard correction factor traditionally taught was a 1.6 mEq/L drop in sodium for every 100 mg/dL rise in glucose. However, modern empirical data (Katz/Hillier) suggests a steeper correction factor of 2.4 mEq/L is much more accurate when blood glucose exceeds 400 mg/dL.
Katz MA. Hyperglycemia-induced hyponatremia--calculation of expected serum sodium depression. N Engl J Med. 1973;289(16):843-844.
Hillier TA, Abbott RD, Barrett EJ. Hyponatremia: evaluating the correction factor for hyperglycemia. Am J Med. 1999;106(4):399-403.
Disclaimer: The clinical scoring and algorithms on this platform are intended strictly for professional informational purposes. They do not constitute a definitive medical diagnosis, treatment, or clinical decision. The final judgment and responsibility lie with the treating physician.