/SOFA Score

SOFA Score

Sequential Organ Failure Assessment

Respiration (PaO2/FiO2 mmHg)
Coagulation (Platelets ×10³/µL)
Liver (Bilirubin mg/dL)
Cardiovascular (Hypotension)
Central Nervous System (GCS)
Renal (Creatinine mg/dL or Urine Output)

Total Score

0

Low risk of mortality (<10%).

0–6Low
7–9+Moderate
10–14+High
15–24+High

Disclaimer: The clinical scoring and algorithms on this platform are intended strictly for professional informational purposes. They do not constitute a definitive medical diagnosis, treatment, or clinical decision. The final judgment and responsibility lie with the treating physician.

Yasal Uyarı: Bu platformdaki klinik skorlamalar ve algoritmalar yalnızca sağlık profesyonellerini bilgilendirme amaçlıdır. Herhangi bir kesin tıbbi teşhis, tedavi veya klinik karar yerine geçemez. Nihai karar ve sorumluluk hastayı yatak başında değerlendiren hekime aittir.

Clinical Overview

The Sequential Organ Failure Assessment (SOFA) score tracks a patient's status during an intensive care unit (ICU) stay to determine the extent of organ function or rate of failure. Under the Sepsis-3 definitions, an acute change in the total SOFA score of ≥2 points consequent to an infection indicates clinical sepsis.

Clinical Pearl

While a single SOFA score predicts mortality, the 'delta SOFA' (change over 48-72 hours) is prognostically much more valuable. A rising SOFA score despite aggressive resuscitation is a grave indicator of treatment failure.

Pitfalls & Warnings

  • Requires multiple laboratory values (PaO2, platelets, bilirubin, creatinine), making it slower to calculate upon initial ED presentation compared to qSOFA.
  • In patients with chronic organ dysfunction (e.g., CKD or cirrhosis), the baseline SOFA is not zero; the acute change must be calculated from their pre-existing baseline.

Academic References

Vincent JL, Moreno R, Takala J, et al. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. Intensive Care Med. 1996;22(7):707-710.

Singer M, Deutschman CS, Seymour CW, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315(8):801-810.

Disclaimer: The clinical scoring and algorithms on this platform are intended strictly for professional informational purposes. They do not constitute a definitive medical diagnosis, treatment, or clinical decision. The final judgment and responsibility lie with the treating physician.